| 标识符 | 资源中文名称 | 资源英文名称 | 疾病概述 | 制作方法 | 相关文章 |
|---|---|---|---|---|---|
| CSTR:16397.09.0M02001422 | 线粒体基因ND2(G3992A)突变大鼠 | SD.Rosa26(tm-CAG-LSL-MT-ND2(G3992A))-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001421 | 线粒体基因ND1(G2996A)突变大鼠 | SD.Rosa26(tm-CAG-LSL-MT-ND1(G2996A))-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001420 | 线粒体基因TrnF(G007A)TrnV(G1030A)Trn L2(G11714/5A)突变大鼠 | SD.MT-Trn F(G007A)/MT-Trn V(G1030A)/MT-Trn L2(G11714/5A)-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001419 | 线粒体基因TrnV(G1030A/G1032A)突变大鼠 | SD.MT-Trn V(G1030A/G1032A)-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001418 | 线粒体基因TrnL2(G11714/5A)突变大鼠 | SD.MT-Trn L2(G11714/5A)-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001417 | 线粒体基因TrnV(G1030A)突变大鼠 | SD.MT-Trn V(G1030A)-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001416 | 线粒体基因TrnF(G007A)突变大鼠 | SD.MT-Trn F(G007A)-GC/ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0M02001415 | 线粒体基因TrnE(G14098A)TrnK(G7755A)突变大鼠 | SD.MT-Trn E(G14098A)/MT-Trn K(G7755A)-GC-ILAS | 线粒体相关疾病 |
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Xiaolong Qi , Lei Tan, Xu Zhang , Jiachuan Jin , Weining Kong, Wei Chen, Jianying Wang , Wei Dong, Lijuan Gao , Lijun Luo , Dan Lu , Jianan Gong , Feifei Guan , Wenjie Shu , Xingxu Huang , Lianfeng Zhang , Shengqi Wang , Bin Shen , Yuanwu Ma; Expanding DdCBE-mediated targeting scope to aC motif preference in rat; Mol Ther Nucleic Acids;2023 Feb 26;32:1-12. |
| CSTR:16397.09.0G02001415 | 人源化H2-D1基因敲入模型 | B6/JGpt-H2-D1em1Cin(Humanized H2-D1)/Gpt | 免疫人源化小鼠 |
利用CRISPR/Cas9 技术，将鼠源H2-D基因的exon2-3替换成人源HLA-B*1301 基因的exon2-3，构建表达人源HLA-B*1301抗原结合槽的小鼠模型。 |
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| CSTR:16397.09.0L02001414 | 红色荧光大鼠（Wistar) | WISTAR.Rosa26(tm-imCherry)-GC/ILAS | 心肌病 |
利用CRISPR/Cas9技术将loxp序列插入Isca1外显子的两端 |
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| CSTR:16397.09.0I02001413 | Isca1条件性敲除大鼠 | SD. Isca1 (tm-loxp)-GC/ILAS | 心肌病 |
利用CRISPR/Cas9技术将loxp序列插入Isca1外显子的两端 |
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| CSTR:16397.09.0H02001412 | CST7敲除大鼠 | SD. CST7 (TM )-GC/ILAS | 神经系统相关疾病 |
利用CRISPR/Cas9技术敲除CST7基因。 |
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